Shargel and Yu's Applied Biopharmaceutics & Pharmacokinetics, 8th Edition

The authoritative textbook on the principles and practical applications of biopharmaceutics and pharmacokinetics

Shargel & Yu''s Applied Biopharmaceutics & Pharmacokinetics has been the standard textbook in its field for over 40 years. This eighth edition includes recent scientific developments in the field and embodies the collective contribution of experts with deep knowledge and experience in the selected subject areas. Shargel & Yu''s Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition provides the reader with a fundamental understanding of biopharmaceutics and pharmacokinetics principles that can be applied to patient drug therapy and rational drug product development.

Shargel & Yu''s Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition has been expanded and revised to include advancements in biopharmaceutics and pharmacokinetics. The chapter sequence has been reorganized into four main sections, providing a more logical sequence for students. The textbook starts with fundamental concepts, followed by application of these principles to optimize drug therapy and to the rational development of drug products. Each chapter includes theoretical concepts with practical examples and clinical applications. Frequently asked questions provide a discussion of overall concepts.

Features:

• Expanded and revised chapters to include scientific advances in biopharmaceutics and pharmacokinetics
• Four main sections providing a natural buildup of knowledge: introduction to biopharmaceutics and pharmacokinetics, fundamentals of biopharmaceutics, pharmacokinetic calculations, clinical pharmacokinetics and pharmacodynamics, and biopharmaceutics and pharmacokinetics in drug product development
• Additional chapters for this edition include:

  o Physiological factors related to drug absorption

  o Approaches to pharmacokinetics and pharmacodynamics calculations

  o Novel and complex dosage Forms

  o Clinical Development and Therapeutic Equivalence of Generic Drug and Biosimilar Products

  o Pharmacokinetics and Pharmacodynamics in Clinical Drug Product Development

• Additional information on drug therapy, drug product performance, and other related topics
• Frequently asked questions, practice problems, clinical examples and learning questions