William A. Craig
Microbiology and Pharmacokinetics
Charles H. Nightingale and Takeo Murakawa
In Vitro Antibiotic Pharmacodynamic Models
Michael J. Rybak, George P. Allen, and Ellie Hershberger
Animal Models of Infection for the Study of Antibiotic Pharmacodynamics
Michael N. Dudley and David Griffith
B-Lactam Pharmacodynamics
JoCarol J. McNabb and Khanh Q. Bui
Aminoglycoside Pharmacodynamics
Myo-Kyoung Kim and David P. Nicolau
Pharmacodynamics of Quinolones
Robert C. Owens, Jr. and Paul G. Ambrose
Glycopeptide Pharmacodynamics
Gigi H. Ross, David H. Wright, John C. Rotschafer, and Khalid H. Ibrahim
Macrolide, Azalide, and Ketolide Pharmacodynamics
Charles H. Nightingale and Holly M. Mattoes
Metronidazole, Clindamycin, and Streptogramin Pharmacodynamics
Kenneth Lamp, Melinda K. Lacy, and Collin Freeman
Tetracycline Pharmacodynamics
Burke A. Cunha and Holly M. Mattoes
Pharmacodynamics of Antivirals
G. L. Drusano, Sandra L. Preston, and Peter J. Piliero
Antifungal Pharmacodynamics
Michael E. Klepser and Russell E. Lewis
Human Pharmacodynamics of Anti-Infectives: Determination from Clinical Trial Data
George L. Drusano
Antibacterial Resistance
Philip D. Lister
Basic Pharmacoeconomics
Mark A. Richerson and Eugene Moore
Utilizing Pharmacodynamics and Pharmacoeconomics in Clinical and Formulary Decision Making
Paul G. Ambrose, Annette Zoe-Powers, René Russo, David T. Jones, and Robert C. Owens, Jr.
Index
This up-to-the-minute reference explores the pharmacodynamics of antimicrobials as well as the absorption, distribution, metabolism, and elimination of the major classes of antimicrobials-covering new agents such as ketolide antibiotics and highlighting the pharmacodynamic relationship between drug concentration and antimicrobial activity, as well as the relationship of pharmacodynamics to bacterial resistance.
Contains specific examples and practical applications for the design of effective dosing regimens!
Written by recognized experts in the field, Antimicrobial Pharmacodynamics in Theory and Clinical Practice describes
the pharmacodynamic properties of all major classes of antibiotics
parameters for microbiological activity of antimicrobial agents such as minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC)
serum/tissue protein binding and penetration rates
differences between in vivo and in vitro postantibiotic effects (PAE)
and more!
With nearly 1000 references, tables, drawings, and illustrations, Antimicrobial Pharmacodynamics in Theory and Clinical Practice is a state-of-the-art reference for infectious disease specialists, pulmonologists, pharmacists, pharmacologists, microbiologists, biological chemists, epidemiologists, internists, and students in these disciplines.
